Chinese medicinal plants for the potential management of high-altitude pulmonary oedema and pulmonary hypertension
نویسندگان
چکیده
منابع مشابه
High altitude-induced pulmonary oedema.
Almost one mountain trekker or climber out of two develops several symptoms of high altitude illness after a rapid ascent (> 300 m/day) to an altitude above 4000 m. Individual susceptibility is the most important determinant for the occurrence of high altitude pulmonary oedema (HAPE). Symptoms associated with HAPE are incapacitating fatigue, chest tightness, dyspnoea at the slightest effort, or...
متن کاملPathogenesis of high-altitude pulmonary oedema.
We have read with great interest the paper by WEST et al. [1], regarding the stress failure mechanism of pulmonary capillaries in the pathogenesis of high-altitude pulmonary oedema (HAPE), and would like to add some considerations. HACKETT et al. [2] described a high incidence of HAPE in subjects without the right pulmonary artery. Recently, we have reported a case of unilateral, left sided HAP...
متن کاملHigh-altitude pulmonary hypertension.
High-altitude pulmonary hypertension (HAPH) is a specific disease affecting populations that live at high elevations. The prevalence of HAPH among those residing at high altitudes needs to be further defined. Whereas reduction in nitric oxide production may be one mechanism for the development of HAPH, the roles of endothelin-1 and prostaglandin I₂ pathways in the pathogenesis of HAPH deserve f...
متن کاملUltrastructure of high altitude pulmonary oedema.
Heath, D., Moosavi, H., and Smith, P. (1973). Thorax, 28, 694-700. Ultrastructure of high altitude pulmonary oedema. When rats are exposed for 12 hours to simulated high altitude corresponding to the summit of Mount Everest, they develop ultrastructural changes in the lungs. These consist of the formation and protrusion of multiple endothelial vesicles into the pulmonary capillaries. It seems l...
متن کاملHaemodynamic studies in high altitude pulmonary oedema.
The clinical and pathological features of acute pulmonary oedema of high altitudes have been the subject of several recent reports (Houston, 1960; Hultgren et al., 1961; Penialoza, 1962; Arias-Stella and Kruger, 1963; Nayak, Roy, and Narayanan, 1964; Menon, 1965; Singh et al., 1965), but the haemodynamic effects of the illness are not well delineated (Fred et al., 1962; Hultgren et al., 1964). ...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2020
ISSN: 1388-0209,1744-5116
DOI: 10.1080/13880209.2020.1804407